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Suppression of autophagy by extracellular vesicles promotes myofibroblast differentiation in COPD pathogenesis

Several redoxin inhibitors induce ferroptosis, such as the already mentioned Trx inhibitor ferroptocide

Simultaneously, ULK1 is activated by autophosphorylation, which triggers phosphorylation of its substrates ATG13 and FIP200 ( Figure 1 Another regulator of autophagy is the energy-sensing protein kinase AMPK